PAMM

Penalized estimation of complex, non-linear exposure-lag-response associations

We propose a novel approach for the flexible modeling of complex exposure-lag-response associations in time-to-event data, where multiple past exposures within a defined time window are cumulatively associated with the hazard. Our method allows for …

Penalized Estimation of Cumulative Effects

On the use of piece-wise exponential additive mixed models for the estimation of cumulative effects in survival analysis.